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Tris-Cl (Tris Hydrochloride): Tris-Cl refers to a solution of Tris (tris(hydroxymethyl)aminomethane) base that has been titrated with HCl to a specific pH. It is used to maintain a stable pH in the solution where as,
Tris-HCl (Tris Hydrochloride): Tris-HCl is a specific form of Tris that is already in the protonated form with HCl, making it a salt. It is commonly used to prepare buffers with a specific pH.