Hi, I have certain doubts in electrophysiology. Why is the resistance of the voltmeter recording the current from the membrane kept high? What is the rationale behind it?
What are rectifying currents? How is it reduced by increasing the concentration of the electrolyte in the pipette?
What is voltage noise? How is this prevented by using a highly concentrated electrolyte solution in the pipette?
How does a concentrated electrolyte solution in the pipette provides a wider recording bandwidth?
I am new to the field of electrophysiology. During my study I had doubts regarding the above points. Please clarify so that I can understand the concepts better. Thank you.