CRISPRi vs. RNAi — Criteria for choosing the Right Approach

[BarryArmstrong]

Hi All

For functional genomics, I’m debating between RNAi and CRISPRi for silencing. How do you decide which platform to use in your experiments?"

Can somebody answer this query…

Thanks

[HarmanAulakh (Harmandeep Kaur)]

Hi Barry

RNAi works well for quick, temporary knockdowns but can be messy. CRISPRi is better if you want clear and lasting gene silencing.

Thnks