# List of Oncogenes/ Oncoproteins

**URL:** <https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544>\
**Category:** Blood\
**Created:** [September 1, 2024, 6:30pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544 "2024-09-01T18:30:00Z")\
**Posts on this page:** 10\
**Page:** 1

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**Author:** ![ARGERINE](https://avatars.discourse-cdn.com/v4/letter/a/8491ac/32.png) [@ARGERINE](https://scientistsolutions.discourse.group/u/ARGERINE)\
**Post date:** [September 1, 2024, 6:30pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/1 "2024-09-01T18:30:00Z")

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How many Oncogenes/ Proto-oncogenes (Onco-proteins) are known in case of humans? If there is a source, provide Link.

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:45pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/2 "2024-09-24T20:45:09Z")

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:45pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/3 "2024-09-24T20:45:33Z")

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:47pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/4 "2024-09-24T20:47:22Z")

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:47pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/5 "2024-09-24T20:47:34Z")

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:47pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/6 "2024-09-24T20:47:54Z")

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**Author:** ![harmandeep1618](https://yyz2.discourse-cdn.com/flex004/user_avatar/scientistsolutions.discourse.group/harmandeep1618/32/23_2.png) [@harmandeep1618](https://scientistsolutions.discourse.group/u/harmandeep1618)\
**Post date:** [September 24, 2024, 8:48pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/7 "2024-09-24T20:48:02Z")

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**Author:** ![Navneet](https://avatars.discourse-cdn.com/v4/letter/n/8e8cbc/32.png) [@Navneet](https://scientistsolutions.discourse.group/u/Navneet)\
**Post date:** [November 24, 2025, 7:06pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/8 "2025-11-24T19:06:57Z")

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Argerine

Were you able to figure out if there is a curated / non curated database of known set of Oncogenes and Proto-Oncogenes or Cancer Biomarkers ?

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**Author:** ![ARGERINE](https://avatars.discourse-cdn.com/v4/letter/a/8491ac/32.png) [@ARGERINE](https://scientistsolutions.discourse.group/u/ARGERINE)\
**Post date:** [November 24, 2025, 7:17pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/9 "2025-11-24T19:17:49Z")

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Navneet

These are the sources we use and refer to.

### **COSMIC – Cancer Gene Census (CGC)**

- The most widely referenced catalog of _experimentally validated_ cancer-driving genes.

- Includes oncogenes, tumor suppressors, mutation types, functional annotations, and evidence levels.

### **OncoKB**

- A precision-oncology knowledge base curated by Memorial Sloan Kettering.

- Classifies genes as oncogenes, tumor suppressors, and gives evidence levels for clinical actionability.

- Strong clinical relevance.

Hope this will help you. Let me know if you need any further information regarding the above.

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<div class="post-metadata">

**Author:** ![ARGERINE](https://avatars.discourse-cdn.com/v4/letter/a/8491ac/32.png) [@ARGERINE](https://scientistsolutions.discourse.group/u/ARGERINE)\
**Post date:** [January 20, 2026, 7:27pm UTC](https://scientistsolutions.discourse.group/t/list-of-oncogenes-oncoproteins/544/10 "2026-01-20T19:27:00Z")

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An Update:

With our work, we are assuming that total tumor progression related gene number is going to be under 1000 with approx 350 to 400 belonging to each category of Oncogenes and Tumor Suppressor Genes. About 100 to 200 are expected to play dual role.
