# Cytokine stability in whole blood

**URL:** <https://scientistsolutions.discourse.group/t/cytokine-stability-in-whole-blood/604>\
**Category:** Cytokines / Inflammation\
**Created:** [January 4, 2025, 7:55am UTC](https://scientistsolutions.discourse.group/t/cytokine-stability-in-whole-blood/604 "2025-01-04T07:55:46Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![sachinsharma95](https://avatars.discourse-cdn.com/v4/letter/s/71c47a/32.png) [@sachinsharma95](https://scientistsolutions.discourse.group/u/sachinsharma95)\
**Post date:** [January 4, 2025, 7:55am UTC](https://scientistsolutions.discourse.group/t/cytokine-stability-in-whole-blood/604/1 "2025-01-04T07:55:46Z")

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Hi, I’m wondering if whole blood samples kept at 1-6 C for 24 hours immediately after draw and then separated into serum and plasma and stored at -80 C for X amount of time would still be appropriate for ELISA testing for cytokines. I understand the half-life of cytokines to be about 60 minutes but wonder if reduced temperature, even in whole blood, would suffice to maintain a similar cytokine level as to what existed originally. Thanks